What is Hackers' Pub?

Hackers' Pub is a place for software engineers to share their knowledge and experience with each other. It's also an ActivityPub-enabled social network, so you can follow your favorite hackers in the fediverse and get their latest posts in your feed.

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Feeling completely brain-shattered by my whole epic Rust-ed coding adventure. What even was that? I have no idea. Still processing it.

Even more crazy is that I have the whole affair recorded end-to-end. Both on video and as a complete terminal history. All of the coding, debugging, testing, and refactoring is there. I'm figuring out what to do with that.

For now though.... sleepy time.

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HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

Link: eurosurveillance.org/content/1
Discussion: news.ycombinator.com/item?id=4

Eurosurveillance | Human papillomavirus prevalence in first, second and third cervical cell samples from women HPV-vaccinated as girls, Denmark, 2017 to 2024: data from the Trial23 cohort study

BACKGROUND Danish women vaccinated with the 4-valent human papillomavirus (HPV) vaccine (HPV types: 6/11/16/18) at age 14 in 2008 reached screening age in 2017, allowing assessment of long-term effects on prevalence, persistence and incidence of HPV infections. AIM To examine the HPV status of cervical samples over time among women vaccinated as girls. METHODS Between February 2017 and February 2024, residual material from cytology-analysed samples collected through the ‘Trial23’ study, part of the national screening programme, was tested for HPV16/18 and non-vaccine high-risk (HR) HPV types. Prevalence in first, second and third samples, and persistence and incidence between samples were calculated. RESULTS Over 7 years, 8,659 women provided at least one sample, 5,835 at least two and 2,461 at least three. In 7,800 vaccinated women, HPV16/18 prevalence was 0.4% (95% confidence interval (CI): 0.2–0.5), 0.3% (95% CI: 0.1–0.4) and 0.2% (95% CI: 0.0–0.4) in three consecutive samples. Prevalence of non-vaccine HR HPV was 32% (95% CI: 31–33), 28% (95% CI: 27–29) and 31% (95% CI: 29–33). Persistence of HPV16/18 and non-vaccine HPV among vaccinated women was 40% and 53%. In adjusted analyses comparing vaccinated vs unvaccinated women, incidence was significantly lower for HPV16/18 (adjusted relative risk (aRR) &lt; 0.10) while incidence of non-vaccine HR HPV types was higher (aRR: 1.66; 95% CI: 1.12–2.45). No significant difference was observed for persistence. CONCLUSION Our study provides real-world evidence of stable protection against HPV16/18 infections in women vaccinated as girls. Less intensive screening seems reasonable until women vaccinated with the 9-valent vaccine reach screening age, when screening should be reconsidered.

www.eurosurveillance.org

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we've built our global economy on the premise that software has a certain bar of quality, which as it turns out was based only on the goodwill of early enthusiast programmers.

now that the market has caught up and erased the negotiation power software engineers once enjoyed, the world is careening head first into a harsh reality of bug-ridden, adversarial software at odds with everyday life.

free software is still our north star. it's more important than ever.

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1/3일자 방송 시작함.

지금 부국장 계정으로 음악방송서버 테스트 중인데 같이 들으실 분. 이 앱 깔아서 제 방송국 접속하면 나오는 듯.

주력은 추억의 애니,게임 음악 등. 앱 상에 검색해서 (검색어 : 네오) 나온 방송 헤더 헤드폰 모양 누르면 음악 나옵니다.

지금 방송 중인 곡들은 제 추억의 애니, 게임음악곡들. 리스트가 리셋 되었기에 신청곡 받습니다. (있으면 틈. 90년대~2000년대 초,중반 곡들이 많이 있습니다.)

앱의 신청곡 란에 제목 쓰면 제 화면에 나오니 그렇게 해도 됨.

노래 제목은 나오게 설정해 달라고 해서 플레이어에서 제목 나오게 설정했고, 작품명이나 가수명은 대체로 안 나오는 편이니 궁금하심 물어보세요.

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Bundler가 uv만큼 빠를 수 있을까?
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- *Bundler의 성능 한계* 를 분석하며, Python의 패키지 관리자
uv 가 빠른 이유를 비교
- uv의 속도는 Rust 언어 때문이 아니라 *병렬 다운로드, 글로벌 캐시, 메타데이터 기반 의존성 처리* 등 구조적 설계 덕분임
- Bundler는 *다운로드와 설치 과정이 결합되어 있어 병렬 처리에 제약* 이 있으며, 이를 분리…
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https://news.hada.io/topic?id=25520&utm_source=googlechat&utm_medium=bot&utm_campaign=1834

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