Are you getting notifications from a thread that you don't care about? Do you want to stop those notifications?
You can do this by using Mastodon's "Mute conversation" feature:
1. Log in through your server’s website or web app
2. Go to a notification you’ve received from the thread you want to mute
3. Click ⋯ on the notification and select "Mute conversation"
No one will know you've done it, and it will only affect notifications from that thread.