I have been working on aehobak, a companion crate to bsdiff[1], a Rust port of bsdiff[2].
crates.io/crates/aehobak/0.0.10

It implements a custom compression format, purposed for in-memory applications. The layout is not frozen, but admits very compact patches.

The first extension beyond transcoding formats is direct application of aehobak patches, which can achieve 75% of memcpy speed and is panic-free.

Direct generation of patches is up next.

[1] crates.io/crates/bsdiff
[2] github.com/mendsley/bsdiff

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