Good to see this new comment from Hilda Bastian 
@hildabastHilda Bastian , on behalf of the Independent Advisory Group for stakeholder engagement on the Cochrane review of exercise therapy for #CFS
"Outdated and misleading content; review unsuitable for clinical decisions"
![Cochrane Database of Systematic Reviews
Exercise therapy for chronic fatigue syndrome
Lillebeth Larun, Kjetil G Brurberg, Jan Odgaard-Jensen, Jonathan R Price | 19 December 2024
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Outdated and misleading content; review unsuitable for clinical decisions
Published : 24 March 2025
Hilda Bastian 0000-0001-8544-7386
This review states that treatment guidelines recommend exercise therapy for people with CFS. This is reflected in a statement in the Plain Language Summary that implicitly encourages use of the intervention: “Exercise therapy is recommended by treatment guidelines and often used as treatment for people with chronic fatigue syndrome.”
This is outdated and misleading.
In support of these statements, the authors cite a NICE guideline for people with ME/CFS that was published in 2007. [1] The NICE guideline was updated in 2021. [2] It no longer recommends exercise as a therapy, and stresses the possibility of harm. Recommendations in other major treatment guidelines are consistent with this, including national guidelines for the US and Germany. [3,4] A systematic review with a search date in October 2022 concluded that data collected in trials “are insufficiently informative to exclude relevant harm due to serious side effects.” [5]](https://assets.disabled.social/media_attachments/files/114/231/313/468/431/586/original/e2f8955f150e3b0f.png)
If your doctor, or the doctor of someone you know, is still suggesting exercise therapy for CFS or fatigue in general, that recommendation has now officially had peer review label it
Outdated and misleading content; review unsuitable for clinical decisions
the full review: https://hbprojecttalk.wordpress.com/2025/03/13/iag-submission/
main author https://mastodon.online/@hildabast h/t 
@tomkindlon
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