So for a long time I found LISP elegant but I found the syntax infuriating. Then I made my own LISP variant with semi-significant whitespace and helper syntax— each line (up to whitespace or comma) is wrapped in an implicit (), a : wraps a () to the end of the line, a {} wraps its interior in (lambda), a [] wraps its contents in (list ), "x.y" becomes "get x y". Suddenly, I found it usable!
I wonder if I could just make an editor that applies these rules implicitly, and then I could use GUIX.